Sigma entered the next decades with broad expansion into biochemicals and clinical products. Within two years, Sigma offered eight additional ATP derivatives and raised purity levels. A small ad in a scientific journal brought orders and Broida expanded production. Berger suggested that Sigma produce the compound on a larger scale and taught his process to Sigma personnel. The Coris and other biomedical researchers at this time were involved in studies requiring ATP in quantity. ![]() ATP is a major source of energy in living organisms and was used extensively in the Cori’s research. As a graduate student, one of Berger’s tasks had been to extract adenosine triphosphate (ATP) from rabbit muscle. Louis School of Medicine under Nobel Laureates Carl and Gerty Cori. In its search for a new direction, Sigma’s turn toward research biochemicals came in the form of Lou Berger, a friend of Broida who had completed a MS degree in biochemistry at the Washington University in St. When the war ended, however, supplies of many raw materials again became plentiful and effectively forced Sigma out of the market. For a year, major distributing companies bought saccharin as fast as Sigma could produce it. To fill the need, Broida formed Sigma Chemical Company as a division of Midwest Consultants. In addition, saccharin was in high demand and short supply. Louis, to manage the company’s growing consulting and production businesses.ĭuring World War II, Midwest manufactured ammunition components and made felt and paper parts for signal flares. The firm incorporated in 1935 and hired Dan Broida, another chemical engineer out of Washington University in St. Louis businesses produce a variety of specialty products including cosmetics, shoe dressings, and adhesives and inks for cardboard packaging. The two chemical engineers named their partnership Midwest Consultants – parent company of Sigma Chemical Company – and began to help St. Louis, MO, when two brothers, Aaron Fischer and Bernard Fischlowitz, launched a small consulting firm. The company’s roots spring from 1934 in St. Every day more than one million customers around the globe count on Sigma-Aldrich for quality products delivered on time and as promised.Ī trusted leader in life science, high technology and service, the story of Sigma-Aldrich has a rich history of innovation. Sigma-Aldrich is the world’s largest supplier of research biochemical and organic chemicals. The company was founded in May 1975 and is headquartered in St. It has a broad global customer base, which includes commercial laboratories, pharmaceutical, industrial, diagnostics, biotechnology and electronics companies, universities, hospitals, governmental institutions and other non-profit organizations. The SAFC unit supplies large-scale organic chemicals and biochemicals used in development and production by pharmaceutical, biotechnology, industrial, diagnostic and electronics companies. The Research Biotech unit supplies immunochemical, molecular biology, cell biology, proteomic, genomic, transgenic and other life science products to academic, government, industrial, biotechnology and pharmaceutical research customers. ![]() ![]() The Research Specialties unit sells organic chemicals, biochemicals, analytical reagents, chromatography and other laboratory consumables, reference materials and high-purity products which are generally sold in smaller volumes to the lab scientist customer. These products are typically sold in higher volumes to value conscious research buyers. The Research Essentials unit sells biological buffers, cell culture reagents, biochemicals, chemicals, solvents, and other reagents and kits. The company operates through four Research business units: Essentials, Specialties, Biotech and SAFC. Sigma-Aldrich’s biochemical and organic chemical products are used in scientific research, including genomic and proteomic research, biotechnology, pharmaceutical development and as key components in pharmaceutical, diagnostic and other high technology manufacturing. It develops, manufactures, purchases and distributes a broad range of biochemicals and organic chemicals. operates as a life science and technology material company. Sigma-Aldrich Corp. history, profile and corporate video
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